CAS:816-94-4|1,2-Distearoyl-sn-glycero-3-fosfokolin

Non: 1,2-Distearoyl-sn-glycero-3-fosfokolin

Sinonim:1,2-Dioctadecanoyl-sn-glycero-3-fosfokolin;(R)-2,3-Bis(stearoyloxy)propyl [2-(Trimethylammonio)ethyl ] Fosfat;DSPC

CAS:816-94-4

Pite: 99 pousan

Fòmil molekilè: C₄₄H₈₈NON₈P

Pwa molekilè: 790.16

Pwen k ap fonn: 236 degre (lit.)

Pwen bouyi: N/A

Aparans: poud blan

Sansiblite: chalè sansib

Estabilite: ki estab. Enkonpatib ak ajan oksidan fò.

Solibilite: Idrosolubl nan dlo; Etanòl: 25 mg / ml

Kondisyon depo: Sere nan -20 degre C

InChi:InChI=1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5){ {14}}(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1

InChi kle:NRJAVPSFFCBXDT-HUESYALOSA-N

Aplikasyon: 1, 2-Distearoyl-sn-glycero-3-fosfokolin(CAS:816-94-4)se yon fosfolipid ki pa pirojenik ki te montre yo fòme lipozom byen defini ki kapab chaje ak yon molekil chwa. Yo rapòte ke sa a chaje ak fòmasyon vesicle akonpli tou senpleman pa yon sèl etap idratasyon. Rechèch te montre ke teknik encapsulation sa a te montre pou ogmante absorption pou 125I ki make polyvinylpyrrolidone pa kat fwa nan yon pweparasyon sak trip de rat granmoun. Plis resamman, konpoze tankou 5-fluorouracil (sc-207031), cyclosporin A (sc-3503) ak celecoxib (sc{-217869) yo te itilize nan teknik sa a enkapsulasyon lipid.

Referans:

1. Rowland, RN, et al. 1981. Biochim. Biophys. Acta. 673: 217-223. PMID: 7213821

2. Malaekeh-Nikouei, B., et al. 2009. PDA J Pharm Sci Technol. 63: 139-148. PMID: 19634352

3. Deniz, A., et al. 2010. Biosci. Rep. 30: 365-373. PMID: 19900165

4. Thomas, AM, et al. 2010. J Kontwòl Release. [Epub devan enprime]. PMID: 21094191

5. Ali, MH, et al. 2010. J. Pharm. Pharmacol. 62: 1646-1655. PMID: 21039548

Anbalaj ak livrezon

Pake: 5g / 10g / 25g / 50g / pake esansyèl

Transpò: pa FeDex oswa pa anbake lanmè oswa kondisyon kliyan

Detay livrezon: Nan 3-5 jou apre peman konplè

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