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CAS:120068-37-3|5-Amino-1-[2,6-dikloro-4-(trifluorometil)fenil]-4-[(trifluorometil)sulfinil]-1H-pirazol{ {9}}karbonitril
Non:5-Amino-1-[2,6-dikloro-4-(trifluorometil)fenil]-4-[(trifluorometil)sulfinil]-1H- pirazol-3-karbonitril
CAS:120068-37-3
Pite: 98%
Fòmil molekilè: C12H4Cl2F6N4OS
Pwa molekilè: 437.15
Pwen k ap fonn: 203.92 degre C (Prevwa)
Pwen bouyi: 510.1 degre C nan 760 mmHg (Prevwa)
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Pwodwi Entwodiksyon
Non:5-Amino-1-[2,6-dikloro-4-(trifluorometil)fenil]-4-[(trifluorometil)sulfinil]-1H- pirazol-3-karbonitril
Sinonim:Fipronil;Termidor
CAS:120068-37-3
Pite: 98%
Fòmil molekilè: C12H4CL2F6N4OS
Pwa molekilè: 437.15
Pwen k ap fonn: 203.92 degre C (Prevwa)
Pwen bouyi: 510.1 degre C nan 760 mmHg (Prevwa)
EINECS:424-610-5
Dansite: 1.477-1.626g/cm3
Aparans: Off blan poud
Solibilite: DMF: 20 mg/ml;DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml;DMSO: 14 mg/ml;Ethanol: 10 mg/ml
Solibilite dlo: 1.9-2.4 mg 1l-1 (20 degre)
pKa:{{0}}.86±0.20(Prevwa)
Λmax: 208nm (H2O) (lit.)
IC50: GABA reseptè alfa-4 sou-inite: IC50 = 2.3 nM (moun); GABA reseptè beta-3 sou-inite: IC50 = 28 nM (moun)
endèks refraktif: n20D 1.62 (Prevwa)
Kondisyon depo: Sere nan tanperati chanm
InChi:InChI=1S/C12H4Cl2F6N4OS/c13-5-1-4(11(15,16)17)2-6(14)8(5)24-10(22)9(7) (3-21)23-24)26(25)12(18,19)20/h1-2H,22H2
Kle InChi:ZOCSXAVNDGMNBV-UHFFFAOYSA-N
Aplikasyon: Fipronil(CAS:120068-37-3)se yon bloke chanèl ki bloke chanèl klori GABA-gated ak chanèl klori glutamate-aktive (GluCls). Nan etid Xenopus ovocyte fipronil bloke repons reseptè GABA yo. Rechèch montre ke fipronil ka ogmante nivo apoptoz nan selil PC-12. Koleksyon 4-n-[3H]propyl-4'-ethynylbicycloorthobenzoate ([3H]EBOB) ak kanal ion klori GABA-gated la inibe pa fipronil nan Drosophila melanogaster.
Referans:
1. Hosie, AM, et al. 1995. Br. J. Pharmacol. 115: 909-912. PMID: 7582519
2. Cole, LM, et al. 1995. Lavi Sci. 56: 757-765. PMID: 7885191
3. Narahashi, T., et al. 2010. Pestic Biochem Physiol. 97: {3}}. PMID: 20563240
4. Hu, XF, et al. 2010. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 28: 264-267. PMID: 20465951
Anbalaj ak livrezon
Pake: 500g / 1kg / 5kg / 10kg / pake esansyèl
Transpò: pa FeDex oswa pa anbake lanmè oswa kondisyon kliyan
Detay livrezon: Nan 3-5 jou apre peman konplè
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