CAS:147126-75-8|Emtricitabine Menthyl Ester

Non: Emtricitabine Menthyl Ester

Sinonim:(2S,5R)-(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl 5-({4-amino-5-fluoro-2- oxopyrimidin-1(2H)-yl)-1,3-oksatiolan-2-carboxylate;(1R,2S,5R)-2-Isopropyl-5-methylcyclohexyl (2S,5S)-5-idwoksi-1,3-oksatiolan-2-karboxylate;

CAS:147126-75-8

Pite: 98 pousan

Fòmil molekilè: C₁₈H₂₆FN₃O₄S

Pwa molekilè: 399.48

Pwen k ap fonn: 180 - 183 degre (desanm)

Pwen bouyi: 508.5±60.0 degre (Prevwa)

Dansite: 1.47g / cm³

PSA: 121.74

LogP: 3.14

Aparans: Blan ak Off-Blan Solid

Estabilite: igroskopik

Solibilite: klowofòm (yon ti kras), metanol (yon ti kras)

pKa:2.40±0.10(Prevwa)

Kondisyon depo: igroskopik, frijidè, anba atmosfè inaktif

Aplikasyon: Emtricitabine Menthyl Ester (CAS:147126-75-8) se yon enpurte Emtricitabine (E525000). Emtricitabine se yon inibitè transkriptaz ranvèse. Li se yon ajan antiviral efikas kont VIH, HBV, ak lòt viris ki repwodui nan yon fason menm jan an. Yon analòg nukleozid ki gen rapò ak Lamivudine (L172500).

Referans:

FASEB J., 13, 1511 (1999), Molina, J.-M., et al.: J. InfecSchinazi, RF, et al.: Antimicrob. Ag. Chemother., 36, 2423 (1992), Shockeor, JP, et al.: Xenobioica, 26, 189 (1996), Feng, JY, et al.:. Dis., 182, 599 (2000)

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Baj popilè: cas:147126-75-8|emtricitabine menthyl ester, pri, sitasyon, rabè, nan stock, pou vann