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CAS 27143-07-3|Asid Acetic, 2-kloro-2-[2-({4-metoksifenil)hydrazinylidene], Ethyl Ester
Fòmil molekilè: C11H13ClN2O3
Pwa molekilè: 256.69
EINECS: 608-053-7
Pite: 97 pousan Min.
Pake: 1 g / 5 g / 25 g / 100 g / 1 kg
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Pwodwi Entwodiksyon
Entwodiksyon
Asid acetic, 2-kloro-2-[2-({4-methoxyphenyl)hydrazinylidene], ester etilik se yon derive ester, ki se yon entèmedyè nan sentèz apixaban.
Spesifikasyon CAS 27143-07-3|Asid acetic, 2-kloro-2-[2-({4-methoxyphenyl)hydrazinylidene], ester etilik
ATIK | SPESIFIKASYON |
pka | 11.63 |
Pwen k ap fonn | 94 degre |
dansite | 1.23 |
tanperati depo. | Sele nan sèk, 2-8 degre |
Pwen bouyi | 349.0 degre |
Sentèz deCAS 27143-07-3|Asid acetic, 2-kloro-2-[2-({4-methoxyphenyl)hydrazinylidene], ester etilik
Kondisyon
Etap #1: 4-methoxy-aniline Avèk idrogenchloride; nitrit sodyòm Nan etanòl; dlo nan 0 - 5 degre ; pou 0.5h; Etap #2: etil 2-kloro-3-oxo-butyrate Avèk acetate sodyòm Nan etanòl; dlo nan 0 - 25 degre ;
Referans
Liu, Ju; Nie, Minhua; Wang, Yanjing; Hu, Jinxing; Zhang, Feng; Gao, Yanlin; Liu, Yajing; Gong, Ping [Ewopeyen Journal of Medikal Chimi, 2016, vol. 123, p. 431 - 446]
Baj popilè: cas 27143-07-3,27143-07-3, asid acetic, 2-kloro-2-[{2-({4-methoxyphenyl)hydrazinylidene], ester etilik, pri, sitasyon , rabè, nan stock, pou vann
