CAS 4684-94-0|6-Asid klowopikolik
Fòmil molekilè: C6H4ClNO2
Pwa molekilè: 157.55
EINECS: 628-517-2
Pite: 97 pousan Min.
Pake: 100 g / 1 kg / 25 kg
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Pwodwi Entwodiksyon
Entwodiksyon
6-Kloropiridin-2-asid carboxylic se yon entèmedyè nan Sorafenib b.
Spesifikasyon CAS 4684-94-0|6-Asid kloropikolik
ATIK | SPESIFIKASYON |
Pwen k ap fonn | 190-191 degre |
InChiKey | ZLKMOIHCHCMSFW-UHFFFAOYSA-N |
tanperati depo. | Kenbe nan yon kote ki fè nwa, sele nan sèk, Tanperati chanm |
koulè | Blan a krèm nan tan |
endèks refraktif | 1.5870 |
fòm | Crystalline poud |
λmax | 294nm (EtOH) (lit.) |
Solibilite dlo | 3.40g/L (tanperati pa endike) |
dansite | 1.3768 |
Pwen bouyi | 241.15 degre |
pka | 3.27 |
Sistèm Rejis Sibstans EPA | 6-Asid kloropikonik (4684-94-0) |
BRN | 115849 |
Referans baz done CAS | 4684-94-0(Referans baz done CAS) |
Sentèz deCAS 4684-94-0|6-Asid kloropikolik
Kondisyon
Etap #1: diyoksid kabòn Avèk o-phenylenebis (diphenylphosphine); Copper(II) acetate monohydrate Nan 1,4-dyoksan nan 65 degre; pou 0.333333h; teknik Schlenk;
Etap #2: 2,6-dikloropiridin Avèk dyasetat Paladyòm; trietilamin; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene Nan 1,4-dyoksan; toluèn nan 100 degre; pou 10h; teknik Schlenk; Tib sele;
Referans
Paridala, Kumaraswamy; Lu, Sheng-Mei; Wang, Meng-Meng; Li, kapab
[Chemical Communications, 2018, vol. 54, # 82, p. 11574 - 11577]
Baj popilè: cas 4684-94-0|6-asid chloropicolinic, pri, sitasyon, rabè, nan stock, pou vann
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