CAS:477600-74-1|N-Methyl-N-((3R,4R)-4-methylpiperidin-3-il)-7H-pyrrolo[2,3-d]pirimidin-4-amine

Non: N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pirimidin{{11} }amine

Sinonim: (3R,4R)-Methyl{(4-methylpiperidin-3-yl)(7H-pyrrolo[2,3-d]pyrimidin-4-yl)}amine; N-Methyl-N-[(3R,4R)-4-metil-3-piperidinil]-1H-Pyrrolo[2,3-d]pirimidin-4-amine

CAS:477600-74-1

Pite: 95 pousan

Fòmil molekilè: C₁₃H₁₉N₅

Pwa molekilè: 245.32

Pwen k ap fonn: 157 - 162 degre

Pwen bouyi: N/A

Aparans: Blan ak Off-Blan Solid

Solibilite: asid akeuz (yon ti kras), metanol (yon ti kras), dlo (yon ti kras, chofe)

pKa:13.36±0.50(Prevwa)

Kondisyon depo: Kenbe nan kote ki fè nwa, Sele nan sèk, 2-8 degre

Aplikasyon: N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pirimidin{{11} }amine se yon sibstans ki itilize nan idantifikasyon sibstans ki gen rapò ak pwodwi degradasyon tofacitinib sitrat lè l sèvi avèk teknik LC-MS pou siveyans pwosesis ak asirans kalite. Yon reyaktif pou sentèz Tofacitinib (CP-690,550), yon inibitè espesifik Janus tirozin kinaz (JAK3).

Referans:

Wu, X., et al.: J. Pharm. Biomed. Anal., 143, 17 (2017); Marican, A., et al.: Tetrahedron Lett., 54, 5096 (2013)

Anbalaj ak livrezon

Pake: 5mg / 10mg / 25mg / 50mg / pake esansyèl

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