CAS 68181-17-9|SPDP
Fòmil molekilè: C12H12N2O4S2
Pwa molekilè: 312.36
EINECS: 269-034-3
Pite: 97 pousan Min.
Pake: 1 g / 5 g / 25 g / 100 g / 1 kg
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Pwodwi Entwodiksyon
Entwodiksyon
SPDP (SPDP Crosslinker) se yon reticulateur chèn kout ki fòme lyezon disulfid clivable (reduibl) ak sulfhydryls cysteine atravè NHS-estè ak pyridyldithiol gwoup reyaktif, reyalize konbinezon an nan amine ak sulfhydryl. SPDP (SPDP Crosslinker) se yon linker ADC clivable ki ka itilize pou fè sentèz antikò dwòg konjige (ADC).
Spesifikasyon CAS 68181-17-9|SPDP
ATIK | SPESIFIKASYON |
Pwen k ap fonn | 84-86 degre (lit.) |
InChiKey | JWDFQMWEFLOOED-UHFFFAOYSA-N |
Tanperati depo. | -20 degre |
Solibilite | asetòn |
Fòm | poud |
Dansite | 1.48 g / cm3 |
Pwen bouyi | 465.9 degre |
pka | 1.76 |
retni | 1548137 |
Referans baz done CAS | 68181-17-9(Referans baz done CAS) |
Sentèz deCAS 68181-17-9|SPDP
Kondisyon
Avèk dicyclohexyl-carbodiimide nan dichloromethane nan 0 degre; pou 2h;
Referans
Horikawa, Ryo; Sunayama, Hirobumi; Kitayama, Yukiya; Takano, Eri; Takeuchi, Toshifumi
[Angewandte Chemie - Edisyon Entènasyonal, 2016, vol. 55, # 42, p. 13023 - 13027]
[Angew. Chem., 2016, vol. 128, p. 13217 - 13221]
Baj popilè: cas 68181-17-9|spdp, pri, sitasyon, rabè, nan stock, pou vann
